The cost of pituitary microadenoma surgery ranges from $40,000 to $80,000 and is divided into two methods: minimally invasive surgery and open surgery, with minimally invasive surgery generally costing less. 1. Minimally invasive surgery: generally transnasal neuroendoscopic surgery, the cost includes the basic surgical cost of about 4,000 yuan, surgical anesthesia cost of about 10,000 yuan, surgical consumables (such as neuroendoscopy, etc.) cost of about 30,000 yuan, and the overall surgical cost of about 40,000 to 50,000 yuan. 2. Craniotomy: Transcranial pituitary tumor resection is less frequently used nowadays. The cost of surgery also includes the basic surgical fee and surgical anesthesia fee of about 15,000 yuan. Due to the fact that craniotomy surgery uses more surgical consumables (such as artificial dura mater, titanium plate, titanium nails, etc.), the cost of surgical consumables is also higher, which is about 40,000 to 70,000 yuan, and the overall cost of the surgery is about 50,000 to 80,000 yuan. In addition, the cost of surgery varies from region to region and from hospital to hospital, so patients can consult their target hospitals for specific costs.