Occasional pain in the stomach in mid-pregnancy is usually caused by contractions, which is not serious and can be observed, but if the pain is frequent, we should go to the hospital in time to do a checkup in order to clarify the specific causes and give targeted treatment. If the pain is not serious, it is usually caused by contractions, which can be observed and generally do not need to be treated. Sometimes it is also associated with other abnormalities such as fibroid degeneration, which need to be examined in the hospital to identify and treat accordingly. Generally speaking, if there are contractions and the uterus becomes hard when the stomach aches vaguely, and the contractions disappear and the uterus becomes soft when the pain disappears, then it is considered to be caused by uterine contractions. Appropriate treatment with contraction inhibitors, such as magnesium sulfate, calcium antagonists, prostaglandin inhibitors, etc., can be given. Patients with a history of uterine fibroids, abdominal pain is often where the fibroids are located, usually this situation should be given antibiotics to fight infection, and then give prostaglandin inhibitors and other symptomatic pain relief. In severe cases, it may also be caused by appendicitis, intestinal cramps, urinary stones, torsion and rupture of pelvic masses, etc., which need to be examined and treated promptly. In addition, the specific use of all the above drugs should be under the guidance of a doctor.