Erythromycin and cephalosporin can be used together. Erythromycin belongs to the macrolide class of antibiotics and is mainly used for respiratory and genitourinary diseases caused by mycoplasma or chlamydia infections. Cephalosporin is an antibiotic of the cephalosporin group, mainly used for the treatment of respiratory diseases, genitourinary diseases and digestive diseases caused by Gram-positive and Gram-negative bacteria infections. The combined application of the two can expand the antibacterial scope, increase the antibacterial strength and promote the recovery of the disease. Do not drink alcohol when taking cephalosporin orally, as alcohol can have a disulfiram-like reaction with cephalosporin. When erythromycin and cephalosporin are used together, patients are advised to drink more water to reduce the adverse drug reactions.