Gas and pain in the stomach can be treated with gastric tablets, cimetidine, omeprazole, and surgery. Most of the manifestations of gas in the stomach with pain in the stomach are caused by gastric hyperdynamia. Many people eat more food or hard-to-digest food in their diet, there will be insufficient gastric power, the stomach can’t digest the food quickly, causing pain in the stomach, which can be treated with gastrointestinal and elimination drugs, gastrointestinal and elimination tablets have the effect of strengthening the spleen and the stomach, helping food digestion, when the accumulation of food leads to epigastric bloating, gastrointestinal dysfunction, which causes stomach discomfort and pain, it can be treated with this kind of drug. When food causes irritation to the stomach, leading to an increase in gastric acid, causing flatulence and pain manifestations, it can be treated by inhibiting gastric acid secretion drugs, commonly known as cimetidine, which reduces the secretion of gastric acid and at the same time relieves the symptoms of gastric discomfort. Omeprazole is belongs to the proton pump inhibitor, after taking it can act on the proton pump in the stomach, can reduce the secretion of gastric acid and relieve the pain in the stomach. Patients with digestive tract obstruction can also trigger the manifestation of stomach distension and pain, and can go to the hospital for gastrointestinal decompression, and consider surgical treatment if necessary.