Grade 3 breast nodules at age 55 are mostly benign and not serious; they are also more serious when there is a 0 to 2% risk of being caused by breast cancer. The BI-RADS classification is a malignancy risk assessment of breast nodules based on the results of ultrasound, mammography, etc. Grade 3 is defined as having a high likelihood of being benign, with a 0-2% probability of being malignant. Grade 3 breast nodules have a >98% likelihood of being caused by benign breast diseases such as breast cysts, hyperplasia, fibroids, etc. They usually only require follow-up and conservative treatment, or they can be treated with surgical excision, and most of them can be significantly improved or cured without seriousness after treatment. Grade 3 breast nodules, which also have some risk (0-2%) of being caused by breast cancer, are more serious. Earlier stage breast cancer may be clinically cured by radical surgery, chemotherapy and endocrine therapy, but more advanced breast cancer is more serious as it affects survival and jeopardizes life. Generally 3 types of nodules can be followed up regularly and treated symptomatically or surgically according to the cause. Patients are advised to consult their specialists for further examination and treatment as prescribed.