With a fever of 38.4°C, if the body is already feeling significantly unwell, you may consider taking antipyretic medication as prescribed by your doctor. Normally, 38.5℃ is considered as the threshold of whether to take antipyretics. The body’s normal axillary body temperature does not exceed 37.2 ℃, so when the body temperature reaches 38.4 ℃, already in a feverish state. If the body temperature of 38.4 ℃, the body has already experienced obvious discomfort, if the condition requires, you can consider taking fever-reducing drugs such as ibuprofen under the guidance of a doctor, to relieve the discomfort of the organism. For the body without obvious symptoms, the body temperature is not more than 38.5 ℃ do not have to take antipyretic drugs, can be used for physical measures to cool down, such as warm water to wipe the skin, cold compresses on the forehead and so on. In short, the use of antipyretic drugs should follow the doctor’s instructions, not blindly use their own drugs, so as not to cause adverse consequences.