Closed pimples, also known as whiteheads, are a typical early skin lesion manifestation of acne. Patients with recurring closed pimples can undergo general treatment, medication and physical therapy. 1. General treatment: patients need to pay attention to not consume greasy, high sugar food, eat more fresh fruits and vegetables, drink more water. In addition, patients need to keep the face clean and dry, do not use irritating soap and keep a happy mood. 2. Medication: Patients can use topical medication such as topical retinoic acid ointment, benzoyl peroxide gel, adapalene gel, etc., which has a certain dissolving effect on closed mouth acne. If necessary, with oral isotretinoin soft capsule, can promote the dissolution of acne and discharge. 3. Physical therapy: when the effect of drug treatment is not obvious, patients can be through the red and blue light localized irradiation and other physical therapy methods, can achieve significant results. All of the above drugs should be used under the guidance of a doctor, patients should not be used on their own, so as not to delay the condition. Patients with recurring closed acne should go to the hospital in time, under the guidance of the doctor for formal treatment.