Vitamin K₃ belongs to the procoagulant drugs in the clinic, which can be used to treat bleeding disorders caused by vitamin K deficiency, such as neonatal bleeding, vitamin K deficiency due to intestinal malabsorption and hypoprothrombinemia. Vitamin K₃ mainly has the effect of antiemetic, antispasmodic and analgesic. Vitamin K is widely available in nature as vitamin K₁, vitamin K₂, and vitamin K₃ is a synthetic, water-soluble menaquinone, which can be taken orally and injected. Vitamin K deficiency can lead to impaired synthesis of coagulation factors, affecting the clotting process and causing bleeding. Vitamin K₃ can treat bleeding disorders caused by vitamin K deficiency. Vitamin K₃ adverse reactions include the following: local redness, swelling and pain; larger doses can cause hemolytic anemia, hyperbilirubinemia and jaundice in neonates and preterm infants; patients with erythrocyte 6-phosphate dehydrogenase deficiency can be induced by acute hemolytic anemia; large doses can lead to hepatic damage, and patients with hepatic insufficiency can be switched to vitamin K₁. The dosage should be based on the disease and follow the doctor’s instructions.