Among patients with congenital heart disease, it is very rare that the cause can be identified. It is very necessary to strengthen the health care of pregnant women, especially in the early stages of pregnancy to enthusiastically prevent rubella, influenza and other rubella viral diseases and to avoid all factors related to the onset of the disease. ”Congenital heart disease is a malformation caused by abnormal development of the heart vessels during fetal life and is a group of birth defects with a high incidence induced by genetic and environmental factors.” The critical period of heart embryonic development is in the 3rd to 8th week of pregnancy, causing congenital cardiovascular malformations also mainly occur at this stage, such as newborns born to mothers with severe viral infections during the 3rd month of pregnancy, especially after rubella virus, have a higher incidence of congenital heart disease. Pregnant women should try to avoid radiation exposure during pregnancy, should not take medication indiscriminately, should seek medical attention when they have a cold, and should do regular maternity checks. Experts remind that currently, more than 70% of pediatric congenital heart diseases can be detected in the embryonic stage through screening and monitoring. Therefore, women in pregnancy must do prenatal screening to be informed of the fetal heart development early.