If the leg pain becomes severe at night while sleeping, it may be due to the fact that many patients do strenuous activities during the day, which may produce an increase in lower extremity pain at night while sleeping. There are also old injuries, such as fractures or soft tissue contusions in the lower extremities, which can cause pain at night after recovery. There is also osteoporosis, which is common especially in the elderly, where lower extremity pain or cramps occur at night. There are also peripheral vascular pathologies, such as deep vein thrombosis or thrombo-occlusive vasculitis, which slow down blood flow at night and can also induce increased pain in the lower extremities. There are also peripheral neuropathies, such as lumbar disc herniation or sciatic nerve pain, which may aggravate the nerve root irritation when lying down or in a particular sleeping position, and then induce the leg pain to worsen at night. If there is no relief in the short term, it is important to go to a regular hospital for further diagnosis and to choose the appropriate treatment.