Neuralgia behind the left ear can be treated with oral oxcarbazepine, carbamazepine, or symptomatic pain relief with gabapentin or phenytoin sodium. Oral lorazepam, clonazepam, or alprazolam may also be used for sedation if the pain is severe enough to interfere with sleep. Sedative drugs have a certain degree of dependence and are generally not recommended for prolonged use. If the patient is not well treated with the above mentioned medications, local closure therapy can also be considered when the pain is severe, usually with the application of botulinum toxin. Most patients may experience symptom relief after closure, mainly due to blocking abnormal nerve discharge. In addition, the main diseases that cause neuralgia behind the left ear include primary occipital neuralgia, but it may also be caused by secondary neuralgia, which commonly includes cranial tumors and can be seen in patients with multiple sclerosis.