Dense shadows in the pancreatic leptomeninges are usually seen in acute pancreatitis, chronic pancreatitis, pancreatic injury and pancreatic head cancer. Pancreatic leptomeninges is a special part of the pancreas, which is the downward protruding tissue of the head of the pancreas, and if it shows high density shadow under CT, it is as follows: 1. Acute and chronic pancreatitis, pancreatic injury: for acute and chronic inflammation of pancreas and pancreatic injury, the tissue at the head of pancreas undergoes a series of changes such as enlargement, edema, necrosis and liquefaction, etc., which will show high density shadow of leptomeningeal area in CT scanning, and the patient will have serious pain symptoms, which will be slowly relieved after symptomatic treatments such as rehydration, antispasmodic, analgesic, etc., and even reach to the healing possibility. 2. Pancreatic head cancer: As the leptomeningeal part of pancreas is the downward protruding part of pancreatic head with special structure, when cancer occurs, there will be high-density shadow in CT scan, and the demarcation is not clear, and the patients often have epigastric pain, jaundice, fatigue, gastrointestinal symptoms such as diarrhea and constipation, which can be diagnosed by puncture biopsy. When it is clear that it is cancerous, surgical treatment should be actively performed. In conclusion, when the high density shadow in the hook of pancreas is found, great attention should be paid to clarify the benign and malignant nature in time and treat it positively so as to avoid delaying the condition.