The main treatments for perimenopausal endothelial shedding include hormone therapy, medication to stop bleeding, and diagnostic scraping. 1. Hormone therapy: perimenopausal endothelial shedding is usually caused by the decline of ovarian function and abnormal hormone secretion level. Hormone therapy can be adopted, and the methods generally used are progesterone, such as: progesterone, dextroprogesterone, etc., which can help the endometrium shedding and reduce bleeding. 2 drugs to stop bleeding: perimenopausal endometrial shedding usually leads to excessive vaginal bleeding, you can use hemostatic drugs to achieve the purpose of auxiliary hemostasis. Such as: tranexamic acid, phenol sulfonyl ethylamine and so on. 3. Diagnostic scraping: If there is a lot of bleeding, diagnostic scraping can also be used for treatment. By removing the uterine lining through surgery, the bleeding can be stopped quickly. Pathologic examination is usually needed after the operation to clarify the nature of the endometrium. At the same time, patients with anemia are given treatment to correct anemia, and medications must be used under the guidance of the clinician to avoid adverse consequences.