Breast enlargement can occur in the whole breast and is one of the more common disorders of hormone metabolism. Breast enlargement may also occur in the location of the paratesticular glands if they are present. Because of the hormonal stimulation in the patient’s body, which leads to overgrowth of the breast tissue, it can cause the patient to develop breast enlargement and mild pain in the breast. For some women, breast enlargement often occurs before menstruation and manifests as unilateral breast pain or bilateral breast pain that goes away with the end of menstruation. Generally speaking, breast enlargement nodules are mostly benign, with clear boundaries and regular shape, which do not require surgical treatment, and regular checkups at the hospital are enough to check the changes of the nodules. If the nodule has increased in size, surgical excision should be considered. Patients with breast hyperplasia should pay attention to diet and work and rest, relax, avoid strenuous exercise, and go to the hospital for checkups if the pain is obvious.