Do long-term antihypertensive drugs hurt your body?

       People originally have the concept of “medicine is three parts poison”, can not take drugs, plus see the drug instructions written so long a long list of adverse reactions, long-term use of drugs are quite worried, refused to use drugs every day, eat stop, resulting in unstable blood pressure, poor control.  The side effects of antihypertensive drugs are overly serious.  Doctors often say that “every antihypertensive drug has side effects”. People interpret this as “antihypertensive drugs are harmful to the body”, which is a bit inappropriate.  Adverse reactions occur only in a small number of people The adverse reactions listed in the instructions are a summary of the various adverse reactions found in the safety tests and long-term clinical observations of the drug, not that all adverse reactions will occur in a person, and not that the adverse reactions mentioned above will definitely occur after taking the drug.  Some of the adverse reactions that are written as “common” actually occur in only 1-10% of people.  Any kind of drug, before being applied to patients, is subject to strict safety testing, if the drug is harmful to the body, it is impossible to pass the approval and appear on the market.  Some serious adverse reactions can only occur under certain conditions.  For example, all beta-blockers (such as metoprolol, bisoprolol, etc.) have “contraindicated in asthmatics” written in their instructions because it’s may cause acute asthma attacks in people who suffer from asthma, not that the drug will give people asthma.  The side effects are not permanent Most of the adverse effects of antihypertensive drugs are reversible, meaning that they can gradually disappear after stopping the drug.  For example, enalapril, captopril and other ACEI drugs may cause a dry cough, and this adverse effect is usually better gradually after switching to ARB drugs such as valsartan and telmisartan.  Some of the adverse effects of antihypertensive drugs can also be offset by the combination of drugs.  For example, calcium antagonists such as nifedipine may cause ankle edema, but when combined with a low dose of ACEI or ARB drugs, the edema can be eliminated and the antihypertensive effect can be enhanced.  The majority of adverse reactions caused by antihypertensive drugs are mild and low in incidence when used rationally, and long-term use of antihypertensive drugs is generally safe as long as blood pressure is well controlled.  Compared with the harm caused by uncontrolled hypertension, the benefits of standardized medication are very obvious, and I hope that you can use the medication reasonably under the guidance of your doctor.