The coagulation quad labs need to be noted for any increase or decrease in them. Coagulation four namely prothrombin time, fibrinogen quantitative, partially activated thromboplastin time and prothrombin time.
1. Prothrombin time: prolongation is usually seen in congenital coagulation factor deficiency, acquired coagulation factor deficiency (e.g. vitamin K deficiency, use of anticoagulant drugs, disseminated intravascular coagulation, etc.); shortening is seen in hypercoagulable state of blood (e.g. thrombosis, multiple myeloma, etc.).
2. Fibrinogen quantification: increase in diabetes mellitus, extensive burns, shock, acute infections, etc.; decrease in cirrhosis, primary fibrinolysis, hypofibrinogenemia, etc.
3. Partially activated thromboplastin time: prolonged in coagulation factor deficiency and fibrinogen deficiency; shortened in thrombotic diseases.
4. Prothrombin time: prolonged in hypofibrinogenemia, increased fibrin degradation products, the use of anticoagulants, etc. Shortening is meaningless.
The four coagulation tests are commonly used in the clinic to determine the presence or absence of coagulation dysfunction, and the indicators should be interpreted under the guidance of a physician.