Alopecia areata (also known as male pattern baldness, androgenetic alopecia) is the most common type of clinical hair loss, manifesting as gradual receding of the frontal hairline, or gradual thinning and loss of hair on the top of the head, mostly in men aged 20-30 years, and some of those suffering from alopecia areata have a family history. The development of androgenetic alopecia is currently considered to be the main cause of genetic factors, which are polygenic, and patients often have a family history, while the maternal family history is often a poor prognostic factor. The pathogenesis is due to an increase in cephalic reductase II activity, which enhances the conversion of testosterone to dihydrotestosterone, resulting in follicular atrophy and hair loss, and thus androgenogenic alopecia is characterized by slow, progressive follicular miniaturization [1, 2]. The most commonly used treatments for this disease are oral finasteride, topical minoxidil solution, or a combination of oral and topical treatments, and hair transplantation. Finasteride, a reductase II inhibitor, was the first oral drug approved by the FDA for the treatment of androgenic alopecia, but it can only be used in men. In a randomized double-blind clinical trial, it was reported that oral finasteride at 1 mg/day for 1 year stopped hair loss in 87% of patients and improved hair loss in 48%, while oral administration for 2 years resulted in an improvement rate of 66% [2, 3]. The literature reports that finasteride treatment for AGA can stop hair loss in about 3-4 weeks, waiting for the final hair to fall out, and it takes 2-3 months for new hair to grow, while taking the drug for 2 years can achieve the best results, but hair loss will continue if the drug is stopped. Minoxidil, originally used for the treatment of hypertension due to its vasodilating effect, is the only over-the-counter drug currently approved by the FDA for the treatment of AGA. There is no definite theory about its mechanism, some reports believe that it can directly stimulate hair follicles, promote the proliferation and differentiation of hair follicle epithelium, and increase its growth; while some people[4] believe that it is related to increasing scalp blood flow Currently, minoxidil solution is available in 2% (Dafixin) and 5% (Mandy), and its improvement rate for 1 year of treatment is about 40%-60%.