Mesenteric lymphadenitis in children can be cured. Treatment of mesenteric lymphadenitis is mainly based on treatment of the pathogen and symptomatic treatment. In children with significant nausea and vomiting, temporary fasting or fluid intake is required, as well as intravenous rehydration. The main symptoms of mesenteric lymphadenitis in children are abdominal pain, nausea and vomiting, which usually occur after an upper respiratory infection. The location of abdominal pain is variable and can be either right lower abdominal pain or periumbilical pain. The pain can be spasmodic or vague, and in a few children it can even be severe. The abdominal pain usually reduces and subsides within 1-4 weeks in children, and in some children it may persist for more than 10 weeks. If mesenteric lymphadenitis is determined to be caused by a bacterial infection and the child has no history of drug allergies, treatment with antibiotics, such as amoxicillin or cefixime, may be prescribed. If the infection is caused by a virus, an antiviral oral solution may be used. If the infection is caused by tuberculosis, anti-tuberculosis drugs, such as isoniazid and rifampin, should be used for treatment. In addition to this, treatment can also be combined with traditional Chinese medicine. TCM treatment is mainly used to regulate the spleen and stomach functions of children through Chinese herbal formulas to improve the discomfort. If conservative treatment is ineffective, surgical exploration is required if necessary. If Salmonella is the cause and an abscess has formed or symptoms of peritonitis are present, surgical drainage is required for treatment.