Nifurtimox capsules are used for the treatment of bacterial, mycotic, and trichomoniasis vaginitis, vulvovaginitis, urinary tract infections, gastrointestinal amebiasis, and trichomoniasis. It is commonly used for the treatment of vaginitis. For more severe vaginitis, the drug can be taken orally, two capsules once, three times a day, for a week, for better results. For mild symptoms, it is usually treated with topical medication, which has fewer side effects. Trichomoniasis and mycotic vaginitis, which can be transmitted through sexual intercourse, should be prohibited from sexual intercourse during treatment. If it leads to cross-infection, the male partner needs to be treated with oral medication at the same time to avoid recurrence. It is important to develop good habits and to scrub both partners diligently before intercourse, and to change underwear regularly.