6-year-old children coughing in their sleep can be seen in physiological phenomena, pathological conditions (such as respiratory tract infections, cough variant asthma, etc.), the intervention needs to be decided according to the cause, such as bronchitis caused by Mycoplasma pneumoniae infection, need to be treated with azithromycin. 1. Physiological phenomenon: If the indoor environment is too high or dry at night, it is easy to stimulate the respiratory tract and cough symptoms, such children often do not have other abnormal symptoms (e.g., fever, wheezing, etc.), and the symptoms can be relieved by paying attention to adjusting the indoor temperature and humidity. 2. Pathologic conditions (1) Respiratory tract infections: such as acute bronchitis caused by Mycoplasma pneumoniae, the cough is obvious at night, and in the early stage of the disease, it is mostly dry cough, and some of the children may be accompanied by fever, and the antibody test of Mycoplasma pneumoniae can be seen as positive. Treatment requires the use of macrolides (such as azithromycin) anti-infective treatment, oral aminoglutethimide oral solution to relieve cough symptoms. (2) Cough variant asthma: these children may have a history of allergy, and their coughs are prolonged, mainly dry, and mostly occur at night, with increased airway responsiveness seen in perfect pulmonary function tests. Treatment requires the use of budesonide and other drugs for nebulization therapy, oral leukotriene receptor antagonists (such as montelukast) to reduce airway reactivity therapy. (3) Other: such as sinusitis at night may appear in the nasal cavity secretion reflux stimulation of the respiratory tract cough, the treatment needs to use antibacterial drugs (such as amoxicillin) anti-infective treatment, and the use of mometasone furoate for local nasal spray treatment. All of the above drugs should be used under the guidance of a physician, and it is recommended to consult a specialist to evaluate the treatment.