It is not recommended to continue drinking alcohol after a duodenal perforation has been treated. Duodenal perforation is mostly caused by duodenal ulcers and is a serious complication of duodenal ulcers. In duodenal ulcers, the mucous membrane of the duodenum can be perforated after severe damage, and even after healing, the mucous membrane is still relatively fragile. Drinking alcohol again will irritate the more fragile mucosa, which will easily lead to damage to the mucosa again, thus causing the duodenal ulcer to recur. Duodenal perforation patients should also pay attention to the diet after healing, to avoid recurrence of the disease. For example, avoid drinking and smoking, develop a good routine, avoid overeating, and maintain a good state of mind. It is recommended that patients with duodenal perforation should follow the doctor’s instructions after treatment, avoid drinking alcohol as much as possible, and consult a doctor promptly after the occurrence of uncomfortable symptoms.