Just as people know that “Panax ginseng” is used for bruises, when it comes to cardiovascular disease, everyone knows aspirin. Aspirin was first known as an antipyretic and analgesic, and has been used for more than 100 years. In the 1980s, scientists studied the role of aspirin in inhibiting platelet aggregation, making it a well-known anti-platelet drug and widely used in clinical practice as a primary and secondary prevention drug for cardiovascular disease. Later, in order to reduce the gastrointestinal side effects of aspirin, aspirin enteric solvent was developed. However, many patients take aspirin at the wrong time, in the wrong way, and in the wrong dosage, resulting in failure to perform well. The following are a few aspects of aspirin “how to eat” for everyone. The actual aspirin is a good way to get the most out of your life. Because coagulation is highest at night, taking aspirin in the morning provides better anti-platelet aggregation and vasodilatation. 2. The main adverse effects of aspirin are mainly gastrointestinal discomfort, and some studies have shown that the incidence of adverse effects is significantly lower in the morning than in the evening. Some scholars believe that the excitement of the vagus nerve of the body is higher at night and the secretion of gastric juice is more vigorous, so if aspirin is taken in the evening, it may strengthen the adverse reactions in the digestive tract. Therefore, patients with coronary heart disease can take aspirin in the morning to strengthen its anti-platelet coagulation effect, while helping to reduce the adverse reactions of the digestive tract. 3. From the human biological clock, the blood viscosity is higher between 6 a.m. and 10 a.m., and the blood pressure and heart rate levels are also high, making this time a high incidence of cardiovascular accidents. Therefore, for the purpose of treatment and prevention of cardiovascular diseases, it is more appropriate to take it from 7:00 a.m. to 8:00 a.m. It is better to take it before a meal than after 1. The traditional usage of aspirin ordinary preparation is to take it after a meal, in order to reduce the direct damage to the mucous membrane of the gastrointestinal tract. Aspirin enteric tablets are coated with an enteric film that resists the acidic environment in the stomach and decomposes only under the alkaline environment in the duodenum, thus avoiding damage to the gastric mucosa. If taken after a meal, the food relieves the acidic environment in the stomach, the acidity of gastric juice increases, and the drug dissolves easily. 2. The mixture of tablets and food prolongs the residence time of the drug in the stomach, which also tends to destroy the enterolysis film and increase the chance of dissolving the drug in the stomach. When aspirin enteric tablets are taken before meals, the drug is not easily dissolved due to the strong acidic environment in the fasting stomach, and the gastric emptying speed is fast after taking it on an empty stomach, so the residence time in the stomach is short, which can reduce the damage to the gastric mucosa. Therefore, it is better to take aspirin enteric tablets before meals. The antithrombotic function of small doses of aspirin is mainly due to its “platelet inhibiting” effect, therefore, it will inevitably increase the chance of bleeding. Finding a balance between bleeding and thrombosis has been a problematic issue. However, studies have shown that 75-100 mg of aspirin has the best antithrombotic efficacy and the least chance of bleeding. When the dose was increased, there was no increase in efficacy, but there were significantly more bleeding events. Therefore, long-term, small doses of aspirin, preferably in enteric form, are recommended. Caution is needed for specific groups of people. There are several conditions or groups of people that require caution with aspirin, and whether or not they need to take it should be judged and selected by the physician, taking into account the clinical risks and benefits. 1). 1 week before surgery 2). After alcohol consumption 3). Pregnant women, those with severe hepatic insufficiency 4). Patients with bleeding tendency, bleeding disorders or low platelets 5). Patients with peptic ulcer, reflux esophagitis 6). Patients with asthma and aspirin allergy 7). Patients who are using vitamin B1, certain hypoglycemic drugs, other anticoagulants (warfarin).