Grade 3 endocervical neoplasia refers to the development of severe heterogeneity and carcinoma in situ of the cervical epithelium. Cervical intraepithelial neoplasia and cervical cancer are sequential processes of change that are bidirectional, meaning they can be downgraded or upgraded. Cervical intraepithelial neoplasia grade 2 is the beginning end of treatment because cervical intraepithelial neoplasia grades 2 and 3 are difficult to define and are treated more aggressively, starting treatment at the presence of intraepithelial neoplasia grade 2. When a woman is found to have grade 3 endocervical neoplasia, she will need to have a conical cervical resection. In addition to treatment, it also has a diagnostic role, which allows her to know whether it is invasive cervical cancer or not, and guides her to the next step of treatment.