Titanium skulls are generally the most stable form of skull and have no unusual side effects. However, every substance may react abnormally with other substances. Therefore, the titanium skull may also have certain intolerance, compatibility abnormalities, that is to say, allergies, so in the process of treatment, must also pay attention to observe the changes in this regard. It is also important to maintain complete asepsis during the surgery, as there is a risk of major problems with this type of implantable skull surgery if there is a certain amount of infection. This is why it is very important to apply antibiotics before the operation, to operate carefully during the operation, and to continue the prophylactic use of antibiotics after the operation. Each person’s skull is different in the extent of the defect and needs to be restored slowly, not all repairs are perfect.