Ankle pain after walking is often caused by osteoarthritis and synovitis of the ankle joint, and the following treatments should be carried out: First, proper rest can reduce the pain of the ankle joint. Secondly, oral medication can be taken to relieve pain, such as meloxicam, celecoxib and loxoprofen sodium tablets, as well as Chinese medicine, such as Gou Qi Zhuang Bone Granules, to treat the pain. Third, physical therapy, microwave physiotherapy or far-infrared physiotherapy, can also relieve ankle pain. Fourthly, external medication can be used to relieve the pain by applying Fotarine ointment or Tongluo pain relief cream.