There is no need to be overly nervous about air bubbles entering the blood vessels during infusion, and if there is less air in the bubble it usually does not cause significant consequences. There have been reports of deaths in humans after 400mL of air injection, but according to research, it takes 2mL of gas per kilogram of body weight to cause death in adults, which means that if an adult weighs 50kg, it takes 100mL of air to cause death, whereas it is usually considered to be 0.2mL/kg, which means that an adult of 50kg is at risk with 10mL of air injected. If an air bubble is seen to enter a blood vessel, the patient can be quickly placed in the left lateral position and given oxygen and medication to improve circulation, and if the patient is experiencing head symptoms then symptomatic management can be carried out until the symptoms resolve.