The prognosis for the acute phase of chronic granulocytic leukemia is extremely poor and survival is extremely short, usually not exceeding one year before death, so allogeneic hematopoietic stem cell transplantation is required in the acute phase of chronic granulocytic leukemia to potentially cure the disease. Allogeneic HSCT is often costly and has a certain transplant-related mortality, and after transplantation, graft-versus-host disease may also exist.