Chinese medicine practitioners believe that heat in the palms and feet is mostly related to yin deficiency, and can choose medicines with the effect of nourishing yin and lowering fire (nourishing the yin essence and lowering the fire), such as Zhi Bai Di Huang Wan (知柏地黄丸). Zhi Bai Di Huang Wan is composed of Zhi Mu, Radix Rehmanniae Praeparata, Radix et Rhizoma Dioscoreae, Radix et Rhizoma Cypress, Cornus Officinalis, Rhizoma Dioscoreae, Rhizoma Dioscoreae, Radix et Rhizoma Ophiopogonis, Poria, and so on. It can be used in the treatment of yin deficiency and fire exuberance (deficiency of yin and essence in the body, resulting in hyperactive fire), hot flashes (a burst of fever), night sweating (abnormal sweating after falling asleep and stopping sweating after waking up), dry mouth and sore throat, tinnitus, and spermatorrhea, among other conditions. It should be noted that the drug should not be taken at the same time with cold and flu medicines. In addition, the drug should be taken with caution for pregnant women. Patients with fever in the palms and feet are advised to go to a regular hospital for treatment under the guidance of a professional physician.