When headache and confusion occur, the cause should first be analyzed and treated for the cause: firstly, many people are prone to headache and confusion when they stay up late, lack of sleep and mental stress, in this case, it is recommended that the patient should supplement sleep in time, which can improve the symptoms. The second aspect, if the patient’s headache confusion is caused by cerebral arteriosclerosis, cerebral blood supply deficiency, you can give the patient symptomatic oral to ibuprofen, blood and brain particles, twenty-five coral capsules of this kind of drugs to relieve headache. Thirdly, if the patient has headache and confusion caused by cold and fever, you can give the patient some anti-cold drugs to improve the patient’s headache and confusion, and suggest that the patient should eat lightly during this period. Fourthly, many people have headaches and confusion due to mental stress and lack of sleep at night can be caused. Patients should mainly relax, reduce stress, exercise properly, work and rest regularly, sleep on time, get up without staying up late and ensure sufficient sleep time. If patients have sleep disorders, such as neurasthenia, they can take oral glutamate and tranquilizer, and if serious, they can take sleeping pills. Fifthly, early brain tumor patients can also show symptoms of headache and confusion. Patients should check the cranial MRI to make a clear diagnosis and then carry out comprehensive treatment.