The causes of high glutamyl transferase are as follows: first, chronic viral hepatitis with long-term recurrent attacks that do not heal, resulting in decreased liver function, liver membrane damage, and impaired aminotransferase metabolism, and increased laboratory results, the patient will also have pain in the liver area, fatigue, discomfort, hate fatty foods, and will also have a decreased appetite and weight loss. Second, recurrent obstruction and infection of the biliary system, commonly in patients with bile duct stones or gallbladder stones, especially after eating and overeating can trigger the appearance of symptoms, and if necessary, surgical treatment is required to remove the obstruction, and to actively control the infection. Thirdly, malignant tumors occurring in the liver, specifically primary liver cancer or metastatic liver cancer, commonly manifested by pain in the liver area and increased transaminases.