Basis for dosage adjustment in hyperthyroidism

The dosage of hyperthyroid medication is adjusted on the basis of the patient’s symptoms, signs, thyroid function, liver function and blood routine. The commonly used drugs for hyperthyroidism in the clinic, including methimazole and propylthiouracil, have a certain risk of liver damage, and some patients will have elevated aminotransferases after using the drugs, and both drugs have the risk of causing granulocytopenia. Some patients may experience a decrease in white blood cells as well as neutrophils, and severe cases may result in granulocyte deficiency, so it is important to check liver function and blood counts on a regular basis. Once liver damage or granulocytopenia occurs, the drug is to be reduced or even stopped. After the application of hyperthyroidism drugs, should also regularly monitor the function of the thyroid gland, check every 0.5-1 month, when there are clinical signs and symptoms of improvement, weight recovery, thyroid function FT3, FT4 fell to normal values, you can consider the reduction of thyroid drugs. It is recommended to follow the doctor’s instructions to adjust the drug dose, do not reduce or stop the drug on their own.