The difference between Dagliflozin and Engeletin lies in the indications, dosage of medication, and medication for renal damage. Dagliflozin and Engeletin are both hypoglycemic drugs, belonging to SGLT-2 inhibitors, which mainly lower blood sugar by promoting the excretion of sugar from urine, and their differences are as follows: 1. Indications: Dagliflozin is suitable for the treatment of adult patients with type 2 diabetes mellitus and patients with heart failure, while Engeletin is only suitable for the treatment of adult patients with type 2 diabetes mellitus. 2. Dosage: The recommended dose of Dagliflozin is 5mg in the morning, independent of food intake, which can be increased to 10mg for those who tolerate the product, while the recommended dose of Emgliflozin is 10mg in the morning, once a day, given on an empty stomach or after food intake, which can be increased to 25mg for those who tolerate the product. 3. Kidney damage medication: with dapagliflozin and engliflozin used in type 2 diabetes mellitus patients to control blood glucose, glomerular filtration rate of less than 45 ml/min patients, both are not recommended, glomerular filtration rate of less than 30 ml/min patients, both are prohibited. However, when dagliflozin is used to reduce cardiovascular risk in patients with heart failure, no dosage adjustment is required in patients with glomerular filtration rates between 30 and 45 ml/min. Dagliflozin and empagliflozin have similar actions and side effects, with adverse reactions such as hypovolemia, diabetic ketoacidosis, uremia and pyelonephritis. Contraindications are dialyzers, patients with severe renal insufficiency. Dagliflozin and Engeletin, when used, should be used according to the doctor’s instructions for the rational use of medication, do not stop the drug during the use of medication.