The differences between vitamin B₂ and B₆ are different roles, different adverse reactions, and different treatment of diseases. 1. Different roles: the role of vitamin B₂ is to be able to promote the body’s metabolism and blood circulation, promote the development of the nervous system, to maintain skin health, but also to promote the absorption of starch, fat and protein. The role of vitamin B₆ is to participate in the normal metabolism of sugars, proteins and lipids, and improve the body’s immune system. 2. Adverse reactions are different: If you use vitamin B₂ excessively for a long period of time, it will cause an overdose of vitamin B₂ in the body, which may cause itching, paralysis, nosebleeds, burning sensation, tingling and other adverse reactions. And vitamin B₆ long-term overdose application can lead to severe peripheral neuritis, neurosensory abnormalities, gait instability, numbness of the hands and feet, as well as drug resistance and other adverse reactions. 3. Treatment of different diseases: vitamin B₂ is commonly used in the prevention and treatment of vitamin B₂ deficiency, such as stomatitis, scrotum, conjunctivitis, etc.. Vitamin B₆ can be used to treat vomiting symptoms caused by pregnancy, radiation sickness and anticancer drugs, and can also be used to treat seborrheic dermatitis. The difference between Vitamin B₂ and B₆ also includes different drug interactions and different pathological effects, etc. Patients are advised to use such medications under the supervision of a doctor to avoid adverse reactions.