Levofloxacin injection dizziness and leg weakness is considered to be an adverse reaction to the drug, need to stop the drug in time, replace the antibacterial drug treatment, and closely monitor the changes in symptoms. Levofloxacin belongs to the quinolone class of antimicrobial drugs, applicable to respiratory infections caused by sensitive bacteria, skin and soft tissue infections, urinary system infections. Its adverse reactions include dizziness, agitation, abnormal liver and kidney functions, etc. It is contraindicated for those who are allergic to the components of the drug, patients under 18 years of age, and pregnant and lactating patients. If dizziness and leg weakness occur after the application of levofloxacin injection is considered to be an adverse reaction to the drug, it is necessary to stop the drug in time, drink more water to promote the excretion of the drug, and closely monitor the change of symptoms, and at the same time, replace the other antibiotics that are sensitive to the causative organisms. Levofloxacin injection needs to be properly applied under the guidance of a doctor, and if there is any discomfort, inform the medical staff in time to adjust the treatment program.