It is possible to use targeted drugs for colon cancer. If distant metastasis, such as liver metastasis or lung metastasis, is found in the examination before surgery, and if distant metastasis is found in the rechecking after surgery, it is necessary to use targeted drugs for treatment. Commonly used targeted drugs are bevacizumab or cetuximab, and the targeted drug treatment also needs to be combined with chemotherapy, which needs to be combined with capecitabine and oxaliplatin. Usually, a systemic examination is needed after 2-3 cycles of the treatment to evaluate the effect of the targeted drug treatment again. If the distant lesions shrink or disappear, the effect of targeted therapy is very good. If the liver or lung metastases do not disappear and continue to progress, the effect of the treatment is a little bit deviated.