If nipple pain occurs every month, consider that the cyclical pain is related to menstruation. Because before the start of menstruation, the level of estrogen in the body will slowly increase, estrogen acts on the estrogen receptors in the breast tissue will lead to breast hyperplasia, which will also cause nipple pain, the end of menstruation when the level of estrogen in the body will decline, breast and nipple pain will disappear, so there will be a few days of pain in the nipple every month, and the phenomenon of the hormone level changes in the body related to the nipple pain. If nipple pain occurs in the non-menstrual period, consider the breast lesions, when the breast has hyperplasia blood circulation accelerated will appear non-menstrual nipple pain, underwear ill-fitting extrusion is also possible. If this kind of situation occurs, it is recommended to check whether the underwear fits well, if it does not fit, it is recommended to change it, if it is not the reason for the underwear, it is recommended to go to the hospital for a breast examination to check whether there is breast hyperplasia and other diseases.