Patients with schizophrenia, who almost always deny that they are ill during the onset of the disease, in the vast majority of cases require mandatory hospitalization for more than 4 weeks, and after their condition improves, they go home to continue taking medication. At this time, the majority of patients take oral medication, which is absorbed through the stomach and intestinal mucosa and enters the systemic blood circulation through the liver to reach the brain for the purpose of controlling psychiatric symptoms. The advantages of this method of drug delivery are convenience, economy, no infection, and relative safety compared with injectable drug delivery, which is the most commonly used method, but because the drug first enters the portal vein and is metabolized by the liver, i.e., the first-pass effect, resulting in reduced bioavailability of some drugs. In addition, coma, vomiting and uncooperative people have difficulty in taking the drug and it is difficult to perform. Intramuscular injection: The drug is absorbed into the blood through the rich blood vessels at the injection site (e.g. gluteus, deltoid muscle), which is more completely absorbed and has a rapid onset of action, and can be injected intramuscularly for those who refuse to take the drug, are noisy and restless, impulsive and aggressive, excited and violent. For some acute patients can be injected intramuscularly short-acting drugs, chronic patients, the need for long-term medication, the patient does not want to take drugs, according to the patient’s physical condition, can be half a month or a month intramuscular injection of long-acting injection, not only to solve the trouble of taking drugs every day, to reduce leakage, hiding drugs and other situations, but also to control the disease, reduce relapse, is a good choice. The above two methods vary from person to person, and the type and dosage of drugs used by patients also vary from person to person, and it is best to choose them under the guidance of a doctor, so that adverse reactions can be dealt with promptly.