Lymph node enlargement can occur during acute HIV infection as well as during asymptomatic HIV infection. However, sometimes the lymph node enlargement is not clearly specific, and the site of appearance, mode of presence, and palpable condition are indistinguishable from ordinary lymph node enlargement. For patients who have AIDS, some of them may develop lymphoma, but there is no obvious specific difference in appearance, only that the patients may have localized nodules or papules, which need to be examined pathologically to be truly diagnosed. Therefore, it is not possible to distinguish whether the patient has AIDS or not simply by virtue of the lymph node enlargement, but to carry out the formal AIDS antibody blood test to confirm the diagnosis, and to carry out blood tests after the window period.