Urine protein 3+ creatinine normal may be caused by glomerulonephritis, nephrotic syndrome or diabetic nephropathy, etc. The early stage of the disease does not affect kidney function, so the blood creatinine can be normal at this time. 1. Glomerulonephritis: mainly manifested as hematuria, proteinuria, hypertension, edema, etc. If it is not accompanied by impaired renal function, urine protein 3+ but normal creatinine can occur. 2. Nephrotic syndrome: early manifestations of large amounts of proteinuria, hypoproteinemia, edema and hyperlipidemia, at this time, there can also be urine protein 3 + creatinine normal. 3. Diabetic nephropathy: diabetic nephropathy is mostly caused by the continuous development of diabetes mellitus, which affects the kidneys, and the patient will have a large amount of proteinuria, and if it is in the early stage of diabetic nephropathy, the creatinine is generally unaffected, and urinalysis can be seen in urinary protein 3+. Urine protein 3 + creatinine normal may also be caused by other reasons, it is recommended to go to the regular hospital in a timely manner, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.