Rotten bedsores can be treated with topical antiseptic and disinfectant or topical antibiotic drugs, such as silver sulfadiazine cream, levofloxacin ointment, and in severe cases, surgery. After the bedsore is rotten, in order to avoid further infection of the wound, it can be treated with topical antiseptic and disinfectant or antibiotic drugs, such as iodine povidone, silver sulfadiazine cream, levofloxacin ointment, and it will also be combined with oral antibiotic drugs to control the infection, such as amoxicillin, cefuroxime and so on. When accompanied by obvious pain symptoms, analgesic drugs such as ibuprofen and diclofenac sodium may be applied. If medication is ineffective and the infection continues to worsen, surgery should be considered if necessary to clean the wound and repair the flap. During the treatment period, it is important to follow the doctor’s instructions to safely apply topical and oral medications, and not to use medications indiscriminately to avoid causing adverse reactions. For underlying diseases, such as cerebral infarction, hypertension, etc., it is necessary to adhere to the treatment, strengthen nutrition and care.