Closed acne, i.e. whitehead acne, can be removed by general treatment, medication and physical therapy. 1. General treatment: patients should pay attention to cleanliness, it is advisable to use warm water and neutral soap to clean the face; avoid squeezing and scratching acne with hands; avoid eating spicy and irritating food. 2. Medication: Common medications include adapalene gel, tazarotene gel, benzoyl peroxide, azelaic acid, isotretinoin and so on. All drugs should be used under the guidance of a professional doctor, and should not be used blindly.