The price of a regular hepatitis B vaccine is about$50-100. The hepatitis B vaccination is given on the same day, then after one month, and then again at six months. Generally, the three doses of hepatitis B vaccine will stimulate the body to produce an immune response and produce hepatitis B surface antibodies. The production of hepatitis B surface antibodies proves that the patient has gone through the self-immune protection mechanism and is immune to chronic viral hepatitis B. Patients should take care to have their blood drawn for hepatitis B triple system after vaccination when appropriate to see if the patient is positive for hepatitis B surface antibodies and the level of antibody titers. If the patient is still negative after three injections of the vaccine, the cause should be further identified and, if necessary, the hepatitis B vaccine can be further boosted until the patient is positive for hepatitis B surface antibodies. It is recommended that patients have a titer of 10 mIU/mL or higher. If the titer is below 10 mIU/mL, the hepatitis B vaccine needs to be boosted. If the patient is 10 years after vaccination, it is also necessary to check the hepatitis B triple system to see if the patient is negative for hepatitis B surface antibody. Because the hepatitis B vaccine is usually consumed about 10 years after injection, patients who have been vaccinated for a longer period of time need to have their hepatitis B triple system rechecked regularly. If the titer of hepatitis B surface antibody is low, it needs to be boosted with further injections.