The location of ascending colon with pressing pain may be colon cancer, ascending colon lymphoma, Crohn’s disease, right ureteral stone and other diseases. Colon cancer and ascending colon lymphoma can be treated with surgery combined with radiotherapy and chemotherapy; Crohn’s disease can be treated with aminosalicylic acid or glucocorticosteroid, and right ureteral stone can be treated with extracorporeal lithotripsy or minimally invasive surgery. 1. Colon cancer: colon cancer is a kind of malignant tumor, cancer cells invade colon tissue, which can lead to pressure pain, often with change of stool character and frequency, emaciation, anemia, etc. Surgery combined with radiotherapy and chemotherapy should be performed. 2. Lymphoma of ascending colon: lymphoma of ascending colon is a kind of malignant tumor of lymphatic system, which often manifests as low-grade fever, night sweating, emaciation, abdominal pain, and pressure pain of ascending colon, and it can be treated with surgery, chemotherapy and radiotherapy. 3.Crohn’s disease:Crohn’s disease is a kind of autoimmune-related inflammatory bowel disease, intestinal inflammation, ulcers lead to pressure pain, often diarrhea, abdominal pain, abdominal mass symptoms, should be given to aminosalicylic acid preparation, such as mesalazine, severe cases can be given glucocorticosteroids, such as prednisone. 4. Right ureteral stone:Right ureteral stone can have pressure pain on the right side of the abdomen, also often have hematuria, lumbago and other symptoms, can be treated by drinking more water, more exercise, extracorporeal lithotripsy or minimally invasive surgery. The location of the ascending colon has pressure pain, there are other reasons, you should go to the hospital, improve the relevant examination to clarify the cause, under the guidance of the doctor according to the cause of the treatment.