If the toothache is accompanied by facial swelling, the majority will gradually subside within 24 hours and there will be a significant reduction in the level and intensity of pain. If the facial swelling combined with toothache remains unrelieved for more than 48 hours, the patient needs to go to the hospital for examination, such as an oral examination for inflammation of the periodontium or teeth, etc. Patients can also have blood tests and other methods to clarify the presence of bacterial infection or viral infection complex. If it is prolonged, the patient can clarify whether it is a bacterial or viral infection through blood analysis, so that targeted treatment, such as the use of antibiotics or antiviral drugs, can eliminate the inflammatory situation more quickly. If the patient is treated with medication and the results are less than ideal, he or she can then go to the hospital for a more in-depth examination to clarify the cause and then more targeted treatment.