Advanced colon cancer requires targeted therapy. In colon cancer patients appear gastrointestinal Zheng symptoms, such as nausea, vomiting, abdominal pain, constipation, difficulty in swallowing, etc., and respiratory symptoms such as cough, difficulty in breathing, etc. There are also neurological symptoms such as insomnia, drowsiness, paralysis, urinary symptoms such as urinary retention, urinary incontinence, etc. There are also systemic symptoms such as fever, bleeding, weakness, edema, etc., and lymph node metastasis symptoms, when patients need to be highly alert to whether they have reached the advanced stage of cancer. For determining the stage of colon cancer, histopathological examination can be conducted, and if the examination result shows advanced stage, targeted therapy is a better treatment method. In early stage, surgery can be performed to remove ward colon or diseased tissues, but in advanced stage of cancer, only chemotherapy or chemotherapy combined with targeted therapy can be used to maintain the patient’s life.