Lumbar spine pain may be an early sign of cancer, but infectious diseases of lumbar spine, ankylosing spondylitis, lumbar spinal stenosis, etc. can also cause lumbar spine pain. 1. Cancer: Generally, the early symptoms of lumbar spine bone cancer are manifested as lumbago, bone pain, pathological fracture, etc. The pain is often difficult to be relieved by standardized treatment. 2. Infectious disease of lumbar spine: such as septic infection of lumbar spine, the local lumbar spine is rich in nerve and blood vessels, when the local septic infection occurs, the inflammation invades the nerves and causes local pain. In addition, it will be accompanied by fever, local redness and swelling. 3. Ankylosing spondylitis: early due to its own spinal inflammatory pain, and lumbar pain, late mainly by the formation of the bone, resulting in patients with limited activity wear and tear or osteoporosis intermittent pain. 4. Lumbar spinal stenosis: due to repeated strain or injury stimulation leads to intervertebral disc degeneration, local muscle stretching endurance decreased, leading to varying degrees of intervertebral disc protrusion or bulging, causing intervertebral stenosis, compression of the nerve root and lead to pain. If lumbar pain occurs, it is recommended to go to the hospital for further relevant examination and timely treatment after a clear diagnosis.