If the diagnosis of hemolytic anemia is confirmed after the first vaccination, the cure of this disease depends on the severity and condition of the patient. Hemolytic anemia after vaccination may be caused by immune hemolysis from the vaccine, or it may be caused by the original disease itself. If the anemia is only mild, the prognosis is generally good. If the symptoms of hemolysis are severe and the anemia is severe, then the condition is critical and treatment is difficult. If hemolytic anemia occurs, it is recommended to go to the hematology department of the hospital for active consultation, to clarify the cause of the disease to give the relevant active treatment, you can use immunosuppressants, hormones and other suppression of immune response, if necessary, to carry out splenectomy or hemofiltration and other treatments. The specific use of drugs under the guidance of a doctor.