One dose of the chickenpox vaccine is not acceptable. The varicella vaccine is a two-dose vaccination that is required according to CDC recommendations, which are used by most healthcare providers in the country. The varicella vaccine 2-dose vaccination can be up to 98% effective and is very effective in preventing chickenpox. Chickenpox is an inflammatory skin disease caused by varicella-zoster virus infection, which is highly contagious, and varicella vaccine is a good preventive measure. Antibodies to the varicella vaccine can persist for a long time, achieving lifelong immunity. Two doses are usually required, with the first vaccination given 12 to 15 months after birth and the second at 4 to 6 years of age. Chickenpox vaccine is unplanned immunization, and it is recommended to consult with the physician at the vaccination site to decide whether vaccination is necessary, taking into account the prevalent areas and seasons, as well as the parents’ own wishes.