The route of penicillin injection includes intravenous drip and intramuscular injection. 1. Intravenous drip: skin test must be done before use, only negative skin test can be applied. It should be used now, and the drip speed should be slow, especially at the beginning, and then adjusted after 10-20 minutes of observation if there is no serious and obvious adverse reaction. 2. Intramuscular injection: It is also necessary to conduct a skin test before use. The site of intramuscular injection is more often chosen in the buttocks. Penicillins, as a class of antibiotics widely used in clinical treatment, are divided into penicillin, benzylpenicillin, amoxicillin, piperacillin and alloxacillin. Penicillin injections are fast acting, have a strong effect on acute infections, and can be administered in a variety of ways. However, the use of these medications should always be in accordance with the doctor’s instructions.