Momofuron is also known as deoxypregnene ethinyl estradiol tablets, the bleeding during the taking of the drug is considered to be related to adverse drug reactions, omission of medication, other diseases and so on. 1. Adverse drug reactions: a small number of patients may experience “breakthrough bleeding” after taking the drug due to insufficient drug dosage or individual differences, which is manifested as a small amount of irregular vaginal bleeding. 2. Omission of medication: Deoxyprogesterone ethinyl estradiol tablets are short-acting contraceptives containing estrogen and progesterone, which play a role in adjusting the menstrual cycle and contraception by inhibiting the gonadal axis of the human body, and omission of the medication may lead to a decrease in the blood concentration of the drug and a decrease in the therapeutic effect, resulting in the endometrium irregularly peeling off the endometrium and the emergence of a small amount of vaginal bloodshed. 3. Other diseases: for the combination of cervical polyps and other organic lesions, there may be bleeding between medications, or even cervical cancer, endometrial cancer and other diseases, if the cancer cells invade the local blood vessels, then there will be vaginal bleeding, and there is no obvious pattern to follow. For patients who bleed during taking deoxypregnene ethinylestradiol, it is considered to be related to the above factors, and it is recommended that the patients go to regular hospitals for consultation and active treatment under the guidance of doctors after clarifying the cause of the disease.